Olanzapine/samidorphan will decrease the extent or result of hydromorphone by pharmacodynamic antagonism. Contraindicated. Samidorphan elicits opioid antagonistic outcomes and will increase risk of precipitating acute opioid withdrawal in patients depending on opioids. In animal replica research, decreased postnatal survival of pups, and reduced entire body weight were observed adheri... https://seymoura381bzu0.webbuzzfeed.com/profile