Substances that don't work as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore sophisticated. GABA-A receptors (RECEPTORS, GABA-A) seem to acquire at the least a few allosteric websites at which modulators act: a site at which BENZODIAZEPINES act by raising the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; http://the-sleepingpills.com